The Battle of the COVID Variants: A Winning Approach

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Meanwhile, other variants are emerging

Predicting which variant will better spread and why continues to be a challenge. Only in-depth studies can provide a better understanding of the factors associated with this spread. According to Charaf Benarafa, “It is with a combination of different in vitro and in vivo models that we were able to consolidate our results to explain the dominance of the alpha variant in immunologically naive populations. Now that a significant proportion of the population is vaccinated, we will also have to consider the impact of immunity on the advantage of new emerging mutants.”

Reference: “Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta” by Lorenz Ulrich, Nico Joel Halwe, Adriano Taddeo, Nadine Ebert, Jacob Schön, Christelle Devisme, Bettina Salome Trüeb, Bernd Hoffmann, Manon Wider, Xiaoyu Fan, Meriem Bekliz, Manel Essaidi-Laziosi, Marie Luisa Schmidt, Daniela Niemeyer, Victor Max Corman, Anna Kraft, Aurélie Godel, Laura Laloli, Jenna N. Kelly, Brenda M. Calderon, Angele Breithaupt, Claudia Wylezich, Inês Berenguer Veiga, Mitra Gultom, Sarah Osman, Bin Zhou, Kenneth Adea, Benjamin Meyer, Christiane Eberhardt, Lisa Thomann, Monika Gsell, Fabien Labroussaa, Jörg Jores, Artur Summerfield, Christian Drosten, Isabella Anne Eckerle, David E. Wentworth, Ronald Dijkman, Donata Hoffmann, Volker Thiel, Martin Beer and Charaf Benarafa, 22 December 2021, Nature.
DOI: 10.1038/s41586-021-04342-0